The phrase "attenuate cell cycle" is correct and usable in written English.
It can be used in scientific or medical contexts, particularly when discussing the modulation or reduction of the cell cycle's progression or activity.
Example: "Research has shown that certain compounds can attenuate the cell cycle, leading to decreased cell proliferation in cancerous tissues."
Alternatives: "reduce cell cycle" or "diminish cell cycle".
Altogether, these results suggest that Brachyury expression may attenuate cell cycle progression, enabling tumor cells to become less susceptible to chemotherapy and radiation in human carcinomas.
Myc overexpression up-regulates genes directed towards cell growth: ribosome biogenesis, protein synthesis, and metabolism [ 49], and Myc has also been shown to repress genes that attenuate cell cycle progression [ 50].
In addition to their role in triggering EMT, transcription factors of the Snail family have been reported to attenuate cell cycle progression by increasing p21 expression (Vega et al., 2004).
Combination therapy, to simultaneously attenuate cell cycle checkpoint control through inhibition of CHK1 while inducing DNA damage with gemcitabine, improved therapeutic efficacy in vitro and in xenograft models of TNBC.
These results suggested that antiestrogen treatments attenuated cell cycle progression, which might contribute to the decrease in long-term expansion.
More recently, it has been shown that (R -roscovitine attenuates cell cycle activation in glial cells, theR -roscovitineg gliattenuatesrmation and micelllial acycletion [22], [23].
Also in the absence of serum, addition of exogenous thromboxane attenuated cell cycle commitment.
At the molecular level, we report that silencing either Id1 or Id3 attenuates cell cycle.
Growth inhibition by rexinoids may operate by attenuating cell cycle progression.
LCMT-1 knockdown attenuated cell cycle progression and caused cell death, so did loss of PP2A holoenzymes.
Our results, demonstrate that Id4 attenuates cell cycle by promoting an S-phase arrest and induces androgen receptor expression.
