Sentence examples for attenuate adaptive responses from inspiring English sources
Given the fact that unilateral nephrectomy increases renal arterial blood flow by ~50% in two days [ 20, 21], it seems that the systemic factors produced by the UUO kidney and/or the presence of renal blood flow in the obstructed kidney attenuate adaptive responses in the contralateral kidney.
While bortezomib 2 was found to effectively inhibit the proteosome, thereby activating UPR-dependent apoptotic cellular mechanisms, the compound has been shown to also attenuate adaptive response cascades in human multiple myeloma cells and select for cells that have reduced expression of secretory proteins.
The parallel strategy is to delete poxviral genes encoding immunomodulators that attenuate adaptive immune responses, but are not required for growth in vitro.
Targeted deletion of the melanopsin gene attenuates these adaptive responses with no apparent change in the development and morphology of the mRGCs.
Early UPR responses attenuate protein synthesis, promoting adaptive responses to restore ER function and to maintain cell survival.
Thus, increased PAI-1 may attenuate the mural adaptive response.
Thus, increased PAI-1 may attenuate a mural, adaptive response to hypertension associated with preservation of endothelial cell function.
Homeostatic outputs are adaptive responses that function to attenuate ER stress and restore ER homeostasis.
Reduced cytokine abundance may attenuate many of the subsequent innate and adaptive responses in the host, including T-cell relevant processes of antigen presentation and expression of co-stimulatory molecules.
Muscles from adult mice show acute increases in stress proteins and regulatory proteins for ROS following contractile activity, and these adaptive responses have previously been shown to be attenuated in muscle from old mice (5, 54, 56).
The association of tibia lead with child DBP in this study was attenuated after adjusting for maternal DBP, suggesting that maternal accumulated lead exposure may also program sex-specific adaptive responses via a maternal BP influence.
