The phrase "attenuate activation of" is correct and usable in written English.
It can be used in contexts related to biology, medicine, or any field discussing the reduction of a response or effect.
Example: "The new drug aims to attenuate activation of the immune response to prevent excessive inflammation."
Alternatives: "reduce activation of" or "diminish activation of".
Triptans attenuate activation of CREB within the central parts of the trigeminal system, thereby leading to potential inhibition of central sensitization.
This effect was markedly suppressed by CD45RB antibody (2.5 µg/mL), suggesting that cross-linking CD45RB may attenuate activation of p38 MAPK induced by LPS.
As activation of RAGE accelerates pathological progression of diabetes or Alzheimer's disease, therapeutic treatments to attenuate activation of RAGE have been suggested [24] and experimented in animal disease or inflammation models [8], [25], [26], [27].
The authors concluded from this correlation that phenotype switching occurred to attenuate activation of the innate immune response....a striking temporal snapshot of the infection process emerged.
Nebulization of plasma-derived AT was found to increase pulmonary levels of AT [ 36, 37], to attenuate activation of pulmonary coagulation [ 36, 37] and to stimulate pulmonary fibrinolysis [ 36].
The mechanisms underlying this transition are unclear, although reported data have led to the proposal that there is an intrinsic defect in Th2 differentiation that is explained in part by allelic variants of the IL-4R, which attenuate activation of STAT6 and induction of GATA-binding protein 3 [ 49], both of which are requisites for commitment to Th2 cell lineage differentiation.
Our data also show that in GES-2 an extensive hydrogen-bonding network between the acyl-enzyme complex and the active site water attenuates activation of this water molecule, which results in poor deacylation by this enzyme.
Interestingly, Nelson and colleagues also found that treatment with a calpain inhibitor attenuated activation of caspase-3 and vice versa [12].
Smaller numbers of larger chylomicrons may explain attenuated activation of factor VII during the postprandial state when the background diet is rich in MUFA.
The presence of UF of EVOO promoted apoptosis and attenuated activation of intestinal and blood T cells isolated from IBD patients, decreasing the frequency of CD69+ and CD25+ T cells and, also, the secretion of IFN-γ.
Compared with the vehicle-treated group, rosiglitazone treatment suppressed production of TNFα at 24 h after TBI, attenuated activation of microglia/macrophages and increased survival of CA3 neurons but had no effect on lesion volume at 21 d after TBI.
