In MS patients, cognitive performance is globally affected and impacts divided attention, focused attention, sustained attention, attentional flexibility, and response speed [ 8, 9].
The cognitive domains considered were processing speed, attention, sustained attention, verbal learning and memory, non-verbal learning and memory, working memory, verbal fluency and executive functions.
▪ Attention will be measured using the Test of Everyday Attention (TEA), [ 50 ] which assesses selective attention, sustained attention and switching attention.
These two networks overlap spatially with a set of regions implicated in processes that require attention sustained over time.
As hypothesized the measures of executive functions, selective attention, sustained attention, and verbal fluency were different depending on the COMT genotype and task demand.
It was hypothesized that measures of executive functions, selective attention, sustained attention, and verbal fluency would be different depending on the COMT genotype and task demand.
An improvement was detected also in the scores of focused attention, sustained attention, visuospatial learning, and spatial short-term memory, although these improvements did not reach statistical significance.
These composite scores include: focused attention; sustained attention; memory recognition and recall; visuospatial learning; spatial short-term memory; executive functions; and mental flexibility.
They were required to focus their attention (sustain an attention score of above 50 for at least 2 seconds) in order to flip the cards; the higher the attention score, the faster they could flip the cards over.
