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Historically, ADA deficiency was the first SCID condition for which a genetic and molecular cause was identified and eventually transplantation of ADA-SCID patients with γ-retrovirus mediated gene-corrected autologous HSCs (from bone marrow or umbilical cord blood) in the early 1990s constituted the first attempts of treating a PID with gene therapy.
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Unless you happened to be on the sharp end of attempts to treat humans like machines – like the workers of Bethlehem Steel – there wasn't an obvious downside.
With the collapse of logical positivism in the mid-twentieth century (and the abandonment of attempts to treat the physical world as a logical construction from facts about sense data), new attention was given to the relationship between sense perception and the external world.
Harnessing the immune system's potent and selective destructive capability is a major focus of attempts to treat cancer.
A number of attempts to treat GD with intravenous ERT (enzyme replacement therapy) were made in the 1970s.
More and more, the questions being asked are "is it worth it?" and if so, "at what cost?." There have been some attempts to assess the costs of treating patients with PAD.
In 1904 the Journal of Obstetrics and Gynaecology (founded in 1902) first described attempts to treat cancer of the vagina and of the breast by X-ray therapy, but the results were said to be disappointing.
Interestingly, several pro-proliferative pathways were up-regulated, which may represent attempts of masitinib treated cells to activate alternative pro-proliferative pathways.
This tissue-preserving strategy has at its core the reduction of treatment-related toxicity by minimising damage caused to the prostate and adjacent structures while attempting to retain the benefits of treating cancer [6 9].
Although not an incremental analysis in itself, this study provides the first attempt to estimate the cost of treating anal cancer in England, and potentially allows for better assessment of the cost-effectiveness of new treatments for anal cancer through the determination of the costs of current best available treatment.
Eurocord said in a statement: "We deplore any attempt to patent a nonpharmacological method of treating patients with hematological diseases and recommend that clinicians and scientists dissociate themselves from patents of this type".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com