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Our initial attempts at crystallizing the full-length Rpn13 failed.
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This property of the structure can at least partially explain why all attempts to crystallize the full-length human small heat shock proteins were so far unsuccessful.
While CDK9/cyclin TQ77R/E96G/F241L crystallizes reliably, attempts to crystallize wild-type cyclin T in complex with CDK9 resulted in very small crystals that proved unsuitable for structural analysis.
The attempts to crystallize the Dpy30 complexed with Ash2LDBM peptide were failed.
Beese says that in previous attempts to crystallize active DNA polymerase, the enzyme was too constrained to do its job.
So the voters register their protests when given the chance, but otherwise remain stymied in their attempts to crystallize an opinion of what solution they ultimately want.
The appearance of these non-native isomers upon complete refolding correlates with the VS ribozyme's incomplete cleavage and heterogeneous equilibrium folding dynamics at the single molecule level [29] and may explain the many failed attempts to crystallize it [28].
Our attempts to crystallize TssK were unsuccessful.
Attempts to crystallize the double and triple variants were unsuccessful.
Attempts to crystallize the compound eventually led to the isolation of tetracyclic digermene 21.
This particular compound was extremely difficult to crystallize, providing unfilterable gels upon attempts to crystallize it from EtOH, EtOH/Et2O, or MeOH/Et2O.
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