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NT-3 delivery has been attempted in model animals [20] [22] with the aim of clinical treatment of hearing impairment, and it would be beneficial to further clarify the mechanism of Slitrk6 action in development of the inner ear and auditory signal processing.
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A comparison is nevertheless attempted in a model problem wherein the initial vorticity distribution is continuous.
This study has demonstrated that, in novice ultrasound users, neither the longitudinal nor transverse approach showed a clear superiority when ultrasound-guided venepuncture was attempted in a model.
MSC-based repair of full-thickness articular cartilage defects has been attempted in animal models, using various carrier matrices [ 111- 115].
To regenerate intervertebral discs, various approaches applying cytokines [ 4, 5], gene transfection [ 6], and nucleus pulposus cells [ 7] have been attempted in animal models.
A targeted approach for enhanced repair using single growth factors embedded in scaffolds has been attempted in animal models in an effort to enhance rotator cuff [ 75] and cartilage repair [ 86].
Other antibody-based therapeutic strategies attempted in animal models have included targeting IL23R, platelet-derived growth factor-receptor, and the TGFβ downstream mediator connective tissue growth factor (CTGF), without any antibody-based therapy in clinical use to date [ 12, 13].
Antibody blockade of IGF-1R has been attempted in breast cancer model systems.
Beside this, immune stimulation by natural products has been attempted in various animal models and in human cancer patients as an adjunct to chemotherapy [ 41].
Beside this, immunostimulation by natural products has been attempted in various animal models and in human cancer patients as an adjunct to chemotherapy [ 24- 26].
Validated CFD models as attempted in this paper are promising to simulation of industrial stirred vessels.
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