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In an attempt to align these efforts, the OBO Foundry (Smith et al., 2007) provides useful guidance on 'best practice' for developing ontologies in the biomedical domain.
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We attempted to align these two Helitrons, excluding the S-receptor kinase and aldose reductase genes.
Global alignment is chosen because we wish to attempt to align the entire 25mer from each sequence.
EXECUTIVE share options were created in an attempt to align the interests of managers and shareholders.
Ironically, this all stems from an attempt to align the interests of executives and shareholders more closely.
If the first attempt to align the BES to the genomic sequence failed, the sequences were reversed and complimented and a second attempt to realign was made.
An attempt to align the three subfamilies failed to identity conserved anchors that would have allowed us to align homologous regions.
By contrast, the RTGS dollar is based floating exchange rate system and its initial rate was set at 2.5 per US dollar, effectively implying devaluation of the local currency, in attempt to align the value with the parallel market rate.
This alignment looks for inversions by attempting to align the query gap sequence to the genomic region bounded by the genomic alignment coordinates of the bases flanking the gap in the original contig-to-genome alignment.
Unfortunately, our attempts to align the available hypervariable partial ORF5 sequences of these divergent EAV strains with homologous regions from other arteriviruses failed due to low sequence similarity.
The anomalous transcript sequences include CDS which explains why attempts to align the rhesus model protein with other species reveal equivalent anomalies (no alignment for amino acids 1 247 and 3683 3730 of the rhesus protein with its human ortholog - [GenBank:NP_056193.2]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com