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Progression onto the next discrimination occurred after attaining criterion of 90% correct performance.
After attaining criterion, the color of the rewarded stimulus image was reversed to the nonrewarded color and 25 trials/day were run again to the same criterion.
Each rat had one training session per day and was trained to a criterion of nine correct trials in one block of 10 trials (binomial distribution p < 0.01, likelihood of attaining criterion in a 10-trial block).
The number of sessions required before attaining criterion performance pre- and postoperatively was calculated for each subject.
Preoperatively there was no difference between groups in number of errors made before attaining criterion performance on either visual discrimination (D1: F = 1.139, D2: F < 1, see Table 3).
However, 5-HT depletions in either locus did significantly impair the acquisition and reversal of a series of novel discriminations, as assessed by the number of errors made before attaining criterion performance (Fig. 3 A).
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C57BL/6J mice took on average ∼15 sessions to reach criterion for Pavlovian discriminated approach, although ∼20% of the original sample failed to attain criterion even with extensive training (>45 sessions) and were excluded from further testing.
The BALB/cJ strain took ∼13 sessions on average to attain criterion for Pavlovian discriminated approach, but with ∼20% of the mice tested being unable to reach the criterion even with prolonged training.
Groups with a higher probability of passing than the control group at this trial interval were quicker to attain criterion, whereas groups with a lower probability of passing were slower to attain criterion.
Additionally there was no difference between groups in number of sessions required to attain criterion performance on the Pavlovian discrimination (F < 1).
Compared with 2005, increase in the percentages of schools meeting each of the 12 accreditation criteria were observed in 2009, except role modeling which dropped slightly to become the second most frequently attained criterion, marginally below play in the shade (Table I).
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