Biological Conservation] criticized our recent advocacy for combining readily attainable metrics of population status to gain insight about relationships between terrestrial plethodontid salamanders and forest succession [Welsh, Jr., H.H., Pope, K.L., Wheeler, C.A., 2008.
The long life spans of most threatened marine vertebrates are combined with delayed reproductive maturity and/or low reproductive rates; these life history traits create the prima facie conditions that make these species at-risk because they sharply limit their maximum attainable rates of population growth.
However, in order to demonstrate equal effectiveness with CCQ score, over 500 patients would have been needed, which is beyond what is attainable in this population.
Co-evolution may however have acted so as to maintain viral replication within the range of growth rates attainable by natural populations of the bacterial host.
In some situations, these sample sizes may not be attainable for natural populations, particularly for threatened and endangered species where both effective and census sizes may be quite small.
The evolution of short-read, high-throughput sequencing technologies has made genomic surveys of large populations readily attainable (23, 24 ).
In this regard, we and several other groups have used human gene expression microarrays to assess the expression of genes in the human airway epithelium, cell populations easily attainable via fiberoptic bronchoscopy [ 4, 9, 12- 15].
The ability to sustain non-lethal variation is evident from the higher mutant loads attainable in EMS TILLING populations for B. rapa[ 33], B. napus[ 34] and wheat [ 35].
Only in this way, a rapid expansion of the modified population would be attainable, judging from our genetic experiment.
The Malawian Ministry of Health (MoH) declared a human resource crisis in 2004 and launched the Six-Year Emergency Human Resources Programme (EHRP) in 2005 [ 7], which attracted major donor funding and aimed to equal Tanzanian staffing levels of 2.3 doctors per 100,000 population (considered an attainable target) by 2010 [ 6, 8].
