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Even when mecA/PBP2′ was induced strongly, ceftobiprole MICs for MRSA only reached 4 mg/L, a clinically attainable concentration.
The maximum attainable concentration of deuterium in steel is C = 1 (at.D/at.met. = 1/1).
The highest attainable concentration of deuterium in steel has been determined to be C = 1 at.D/at.met.
The maximum attainable concentration of deuterium in steel is C = 1 (at.D/at.met. = 1/1) by irradiation at 100 K [42].
For further analysis, [SB] could represent the concentration of ligand bound to the receptor, [F] represents the concentration of unbound ligand or "free" ligand, and B max represents the greatest attainable concentration of bound ligand: frac{{[{text{SB}}]}}{{ [ {text{F}}]}} = frac{{B_{hbox{max} } }}{{K_{text{d}} }} - frac{{[{text{RL}}]}}{{K_{text{d}} }}.
The maximal attainable concentration of caffeine (70 mM) caused an approximately fourfold decrease in IP3 sensitivity (ΔpEC50 = 0.61 ± 0.07).
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Importantly, we conducted our work with physiologically attainable concentrations of both doxorubicin and lovastatin in human cell systems selected to overexpress human P-gp.
In search of novel yet non-toxic TRAIL sensitizing agents, numerous studies have focused their attention on natural agents that could potentiate TRAIL-mediated apoptotic effects at physiologically attainable concentrations.
In addition, physicians should select agents that have rapid bactericidal activity, high attainable concentrations at the site of infection compared with the organism MIC, a relatively low incidence of antibacterial resistance, and a broad spectrum of activity.
Additionally, when exposing some of our cells for long periods of CQ treatment (> 7 d), we observed CQ effects on growth and toxicity for some of our cell types at concentrations well below 5 μM (data not shown), indicating that physiologically attainable concentrations of CQ are sufficient to observe effects on growth and toxicity in cancer cells.
The influence of the distillation column components efficiency on the attainable distillate concentration and the effects of the distillate concentration and the liquid entrainment and blow-down on the system operating conditions and performance are analyzed and quantified.
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