A second generation drug, gemcitabine, has been effective in NSCLC treatment; and in order to attain effective delivery of gemcitabine to NSCLC cells, Ventura et al. in 2011 came up with chitosan-dextran-based delivery system [47].
However, it remains a challenge to attain desired delivery rate at injection sites due to local tissue pressures exerted on the soft hydrogels.
Nonviral gene vectors offer the possibility of improved safety but have generally failed to attain satisfactory delivery efficacy in clinical testing.
Traditionally, ICBT has been considered the main radiation delivery modality to attain suitable dose delivery with techniques and principles that have evolved over decades of observations and experimentation.
The present study is designed and significantly planned to study the effect of double-compression coating on core mini-tablets to attain the chronopharmaceutical delivery of ketorolac tromethamine to colon.
The obtained results showed the capability of the system in delaying drug release for a programmable period of time and the possibility of exploiting such delay to attain colon-targeted delivery according to a time-dependent approach.
High-risk general surgical patients were allocated to post-operative GDT to attain an oxygen delivery index of 600 ml min-1 m-2 or to conventional management.
It concerns human procreation as the principal marital concern and leaves room to insert the name of the woman for whom the ability to conceive and attain successful, painless delivery of children it seeks.
Hence, the major objective of this work was to robustly generate positively charged nanocarrier with size range of <100 nm, so as to attain high intratumoral delivery of anticancer drug by engaging EPR benefit as well as charge-based interactions [ 48].
Aside from charging a pick up and packaging fee, which alone might set off a few unit economic alarm bells, some of Weeng's margin lies in the discounted rates it can attain from its partner delivery companies through bulk purchasing, not all of which is passed on to customers.
The World Health Organization defines a "critical shortage" of health workers as being fewer than 2.28 health workers per 1000 population and failing to attain 80% coverage for deliveries by skilled birth attendants.
