In pat-9 mutants, UNC-52/perlecan, the most upstream molecule of the muscle attachment assembly pathway, is present in the basal lamina; however, PAT-3/integrin is not well organized at the basal membrane.
Cohesin cleavage also presumably abrogates the kinetochore tension that satisfies kinetochore attachment surveillance pathways.
The inactivation of Cdk1 through cyclin B proteolysis at anaphase onset could therefore disable attachment-monitoring pathways when sister chromatids split.
Compared to aerobic sludge, the significantly prevalent SLH domain (Additional file 1: Figure S6) which could anchor onto the bacterial cell wall polymers suggested recurrent incidence of attachment-based pathways in anaerobic sludge.
Based hereupon, one of the theories that Granqvist et al. developed is the correspondence pathway of attachment to God.
These differences in phenotype and localization suggest VAB-19 might act earlier than EPS-8 in a pathway of attachment structure biogenesis.
In particular, we found a significant indirect pathway from romantic attachment avoidance, but not attachment anxiety, to MFR via caregiving.
In addition to the protein degradation pathways, ubiquitin attachment is also implicated in dynamic cellular events, such as the transduction of cellular signals, gene transcription as well as DNA damage and repair (Hunter, 2007; Jackson and Durocher, 2013).
The results of this study also suggest the possibility that Asc10 expression in the context of the core enterococcal genome provides E. faecalis with two potential pathways of attachment and biofilm formation on host tissues such as heart valves.
