Although this method has been successful for some problems, the success of designing complex crystal structures containing many atoms is often limited by the efficiency of the search method utilized.
Additionally, surface energy, a measure of unbonded surface atoms, is often examined to ascertain a material's ability to facilitate osseointegration [ 9, 19].
A block, although can be a cluster of any number of atoms, is often chosen to consist of atoms of a single or several consecutive residues in sequence (Tama et al. 2000).
There are at best four atomic types (considering the non-hydrogen atoms are often carbon, oxygen, nitrogen, or halogen atoms) and, therefore, to express the approximate interactions, MEDV include a maximum of 10 elements (e.g., M11, M12, M13, M14, M22, M23, M24, M33, M34, M44).
Furthermore, his concerns about atoms were often specific to the various competing theories of the time.
However, hydrogen atoms are often visible in the difference Fourier map.
For the atomistic strain calculations, the bonds between atoms are often considered as ideal springs.
The bond type was not considered since equivalent atoms are often part of a resonance structure with delocalised electrons.
In each method, trial partial structures for heavy or anomalously scattering atoms are often obtained by the inspection of difference-Patterson functions or by semiautomated analysis.
Iron atoms are often linked with sulphur in Fe-S clusters in the catalytic core of enzymes involved in diverse functions such as respiration, ATP generation, and DNA replication and repair, which might account for this phenomenon.
Glycosyl donors with leaving groups attached to the anomeric carbon atom are often protected at all of the remaining hydroxyl groups to avoid competition with the acceptor molecule during the glycosylation reaction.
