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Correlation between CNAs detected by array CGH and qPCR was revealed in 4/4 (100%) cases with loss at this specific locus.
Additionally, Masumoto's group demonstrated that histone H3 lysine 9 trimethylation (H3K9me3) prevents de novo CENP-A assembly on HAC alphoid DNA by tethering Suv39h1 (a methyltransferase) at this specific locus in mammalian cells (Ohzeki et al. 2012).
Interestingly, Zhao et al. identified a PRC2-interacting antisense transcript to the 3′ of RARβ2 gene in mouse ES cells suggesting that ncRNA might target polycomb repression at this specific locus.
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However, at this specific loci neither Nsl1, nor Msl1 can be detected.
Number of repeated BRE elements at the specific locus.
‡Numbers in columns 2 through 5 represent the number of repeats at the specific locus.
Missing data were replaced with the most frequent allele at that specific locus for each breed.
Though this hypothesis is very attractive, authors did not show the presence of CSB at these specific loci.
If there were less than three values present in a single group, at a specific locus, then this locus was ignored from the analysis.
ZFRs could be used to promote transgene integration at a specific locus, or deletion of specific genomic DNA segments.
Odds ratios for haplotypes at each specific locus were estimated using calculators at VassarStats [ 33].
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