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Cervical disc replacement (CDR) is a new technology with the aim of addressing the limitations of fusion procession and preserving motion at the treated level.
These devices are designed for placement between adjacent spinous processes and function to create relative segmental flexion at the treated level, indirectly increasing the cross-sectional area of the spinal canal as well as the neuroforamina.
No patient complained of worse pain at the treated level, or experienced any new neurologic deficits.
No patient had relapse of spinal infection at the treated level during the follow-up period (Table 3).
In contrast, traditional decompression procedures utilize an invasive medial-to-lateral approach that removes a significant portion of the posterior elements at the treated level.
The in situ compressibility allows surgeons to control the lordosis at the treated level, while the adjustable sizing allows for an optimized anatomical fit.
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The carcinogenic effect on mice at the treated dose level was DBN greater than BBN greater than BCPN.
No cases of implant migration, subsidence, or refracture at the treated or adjacent levels were reported.
Furthermore, fluorescence recovery reached plateau at a lower level in the treated cells (94.6±0.06% compared to 98.85±0.0.07%).
The results of ELISA also confirmed the down-regulation of CCL2 expression in the treated cells at the protein level.
Ultrasound examinations were performed by a physician familiar with the procedure to obtain ultrasound information on the treated leg at the same level.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com