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Erythroid precursor cells undergo nuclear extrusion and mitochondria degradation in reticulocytes at the terminal step of erythrocyte formation.
This vitamin B12 dependent enzyme catalyzes the isomerization of L-methylmalonyl-CoA into succinyl-CoA at the terminal step of propionyl-CoA oxidation.
By defining the control cost for each control input and terminal cost for each state, the problem is to find a sequence of control inputs that leads the network into desirable states at the terminal step with minimum average cost.
COX is a rate-limiting enzyme present as a dimeric unit participating at the terminal step in respiratory chain to reduce molecular oxygen into water and pump protons across the inner mitochondrial membrane [ 29- 32].
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The terminal step of this sequential process is colonization of the tumor cells at distant sites in the body.
Bcl-2 inhibits one of the terminal steps of apoptosis.
Therefore the network will never stop at those states at the terminal time step.
At the final step, 2-naphthelene acidic acid reacts to the N-terminal tripeptide.
During the reduction of soluble acceptors such as fumarate, protons are consumed at the terminal electron accepting step resulting in a net proton uptake.
In contrast, during anaerobic growth with metals, the protons generated during substrate oxidation cannot be removed at the terminal electron accepting step.
Furthermore, improved understanding of the global proton balance in Geobacter species can provide insights on the physiology of other species capable of extra-cellular electron transfer such as Rhodoferax, Shewanella regardless of the mechanism of the electron transfer since protons are not consumed at the terminal electron accepting step in all cases.
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