Sentence examples for at the single dose from inspiring English sources

Kinase inhibitors at the single dose used in cell growth assays effectively suppress the corresponding downstream signaling.

In the prostate cancer cell lines, PC-3 and DU145, KU174 was cytostatic at the single dose of 10 μM with values of 0.46 and 51.79, respectively.

After the first IV infusion at the single dose of 600 μg/m, OM-174 pharmacokinetic profile showed a Tmax longer than the end of the infusion, a Cmax reaching 394 ng/ml and a two phases elimination process (an initial phase of only a few minutes and a second phase lasting about 22 hr).

24 h after a single dose of estrogen, the LRP2 mRNA level increased more than 4-fold (bar 2 vs. 1); at 48 h after the single dose (bar 3), the level had returned to that in untreated roosters, and remained low for another 24 h (bar 4).

Lipid levels measured at 1 h before dosing in the single dose groups and at 1 h before dose 3 in the multiple dose groups served as baseline values.

The single doses were started at 0.1 mg/kg.

One patient experienced an infusion reaction at the highest single dose, while another developed neutralizing antibodies to LymphoStat-B.

The median change from baseline in CD138+ plasmacytoid cells at day 84 for the single-dose cohorts ranged from a 2.5% increase in the 1.0 mg/kg group to a 1.5% decrease in the 10 mg/kg group.

The median reduction from baseline in CD20+ B cells at day 84 for the single-dose cohorts ranged from 11%to47%7%, whereas a 23% increase was observed in the placebo group.

Simulated SS pharmacodynamic profiles for subjects in both age groups are shown in Fig.  1b, where an upshift in the simulated GIR profile at SS was apparent compared with the single-dose profiles.

Thus the felodipine loaded nanoparticles were found to be orally safe at the single limit dose equivalent to 240 mg/kg body weight of felodipine.