The phrase "at the replication" is correct and usable in written English.
It can be used in contexts related to processes, experiments, or procedures that involve duplication or copying.
Example: "The results were consistent at the replication, confirming the initial findings."
Alternatives: "during the replication" or "in the replication process".
In principle, lesion bypass can take place either at the replication fork or at post-replicative gaps created when replication restarts downstream of an arrested fork.
The inhibition of pathogenic bacteria at the replication stage is important to halt their further reproduction and spread.
We have also excluded the possibility that both inhibitors act at the replication step of virus life cycle.
Therefore, abasic sites resulting from the action of UNG at the replication fork is possibly unlikely to be dealt with by BER alone.
Here, we performed two recombination assays to show that Red recombination between linear dsDNAs and circular bacterial chromosomes takes place at the replication fork by single-strand annealing.
In a model for oligo recombination, λ Beta protein anneals the oligo to complementary single-strand DNA at the replication fork.
We therefore propose that uracil in single-stranded DNA at the replication fork is incised by UNG2 and repaired by recombination or fork regression, which are both processes requiring recombination proteins.
This review summarizes the current state of knowledge of the eukaryotic core replisome proteins, their structure, individual functions, and how they are organized at the replication fork as a machine.
The data suggest the existence of a large molecular machine, the "unwindosome," which separates DNA strands at the replication fork and contains Cdc45, GINS, and the MCM2-7 holocomplex.
How the complex is assembled onto and maintained at the replication origins is not fully understood.
If the inhibitors function at the replication and transcription step, the in vitro enzymatic assays are preferred.
