Sentence examples for at the postsynaptic density from inspiring English sources

NMDA channels were clustered at the postsynaptic density.

If they clustered, for example, at the postsynaptic density, a very different action potential calcium profile would result.

To examine this question we asked whether CaM responded to the very rapid spikes in calcium concentration seen at the postsynaptic density following influx through flickering NMDARs.

The voltage-dependent calcium channels were distributed evenly over the surface of the spine except in one simulation examining the effect of clustering them at the postsynaptic density.

One population of CaM was concentrated at the postsynaptic density and the other was uniformly distributed throughout the spine (Fig. 7upper left illustration).

AKAP5 has been shown to interact with membrane proteins at the synapse as well as scaffolds at the postsynaptic density (PSD) [7].

There is also a close alignment of the active zone with a postsynaptic specialization, known as the postsynaptic density [5], [10].

As shown in Figure 6C, the vast majority of large boutons (∼88%) formed synapses exclusively with CB+ dendritic shafts containing ionotropic N-methyl-D-aspartate receptors (NMDA-NR1) at the synapse or at sites adjacent to the postsynaptic density (Fig. 4E H).

These structural changes can occur at the level of the postsynaptic density, or even the gross morphology and number of dendritic spines.

Interestingly, schizophrenia patients show enriched de novo mutations in genes regulating the postsynaptic density at glutamatergic synapses [58].

There is evidence that the assembly and localization of GluRIIA into the postsynaptic density at the NMJ is accomplished following delivery to the plasma membrane (Broadie and Bate, 1993; Rasse et al., 2005).