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Supervision is necessary to ensure they exercise at the correct intensity, to provide physical and motivational support and to help keep them focused [ 18].
In order to ensure participants are exercising at the correct intensity (moderate or vigorous), all participants wear the Polar Vantage XL (Polar Electro Oy, Kempele, Finland) heart rate monitor during the aerobic exercise sessions in the intensive 12-week program.
Similarly, we acknowledge that while incorporating home-based sessions in the prescription may increase adherence, we believe that it critically important to monitor all exercise sessions to optimize safety and ensure that all sessions were performed at the correct intensity and ensure that the duration of each exercise session is equal between all groups.
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As our model only correct for the bias caused by degradation during amplification at probe level, the corrected intensity didn't perform the background correction or normalization at probe set level.
To calculate the final fluorescence intensity in the presence of an FOL compound, the corrected intensity of the FOL compound alone was subtracted from the corrected sample intensity.
In the next step, the corrected intensity values were transformed into (Δ0,p, Σ0,p -coordinates using the corrected intensities in Eq. (9).
When correction of saturated intensities was performed (see below), the corrected intensities were used in the normalization algorithm.
The corrected intensities are reported in Fig. 1.
This results in a smooth monotonic transformation of the background subtracted intensities such that all the corrected intensities are positive.
A variance-stabilising transformation was applied to the corrected intensities for each array [47].
The corrected intensities are then averaged across the probe set.
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CEO of Professional Science Editing for Scientists @ prosciediting.com