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It has attracted increasing attentions because of broad antibacterial spectrum including antibiotic-resistant bacteria, noncytotoxicity at suitable doses, satisfactory stability, and smaller possibility to develop resistant bacteria [ 25, 26].
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Nanoparticles offer great visions of improved, personalized medicine which has emerged in recent days to enlarge and administer the suitable drug, at suitable dose, at the suitable time to the suitable patient.
In vivo ARP at suitable dose is effective on Th1 cells, as associated with an enhancement of IgG2a and IgG2b levels.
These results suggest that protection occurs at clinically suitable doses of pramipexole.
Following HSC expansion at a suitable dose and, if applicable, ex vivo or in vivo selection for corrected/modified cells, appropriate pretransplantation conditioning (myeloablation) of the patient can eventually be applied before intravenous or intrabone infusion of HSCs.
However, there is not enough data in the literature to evaluate the suitable doses and targets.
Our preliminary screens indicated that drug treatment at IC25 was a suitable dose in that it maintained drug pressure while exhibiting minimal variation in inhibition after each splitting during the 21 d screens.
Preliminary experiments with a series of gentamicin concentrations starting at 0.09 M established 0.56 M as a suitable dose that caused a moderate auditory threshold shift while avoiding major pathophysiology (data not shown).
They were anesthetized by a suitable dose of sodium barbital.
They were anaesthetised by a suitable dose of barbital sodium throughout the entire experiment.
Primary experimental methods can also determine the suitable dose to cure the disease.
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