Sentence examples for at substantial reduction of from inspiring English sources

Sustainable development efforts aimed at substantial reduction of carbon dioxide emissions focused research activities in this field, among others, on a partial or full replacement of Portland cement by environmental more friendly alternatives.

Effective training of ML-based automatic alert adjudication systems can be achieved at substantial reduction of the effort required of expert clinicians.

Basically, the research efforts are focused on two pharmacological strategies [ 23]: one directed at abstinence from - or at least substantial reduction of - cocaine use and the other directed at minimizing cocaine-related harm by replacing short-acting, illicit cocaine by a long acting, legal stimulant that can be taken orally [ 24- 26].

(A ) Immunoblots of whole brain lysates from wild type, heterozygous, and knockout mouse at E18.5 show substantial reduction of synaptic proteins in knockout brain.

Substance abuse including injection drug use was not an exclusion criteria for an interferon-based therapy, however abstinence (or at least a substantial reduction) of alcohol and concomitant substance abuse was strongly recommended in all patients.

Continued use of domestic and cheap natural gas and oil resources for power generation and at the same time substantial reduction of CO2 emissions can only be realized by implementation of Carbon Capture and Storage (CCS) in the electricity sector.

The second bailout is to be "financed through both official and private sources … in the form of informal and voluntary roll-overs of existing Greek debt at maturity for a substantial reduction of the required year-by-year funding within the programme, while avoiding a selective default for Greece", the eurozone ministers said.

Treatment of the receptor-positive breast cancer cells (BT474 and MCF7) with rapamycin resulted in a rapid inactivation of the mTOR downstream molecule p70S6K, evidenced by a decrease in phospho-p70S6K at Thr389, and a substantial reduction of oxygen consumption, suggesting that the mTOR/p70S6K pathway was important for maintaining mitochondrial respiration in these breast cancer cells.

Root hairs incubated with 10 μM 2-BP for 2 3 hrs showed the most substantial reduction of CBL2 at the tonoplast and at 12 hrs showed complete absence of tonoplast-CBL2.

Positrons are trapped at defect sites causing a substantial reduction of the diffusion length and a slight increase of the S parameter.

The effects of the added compounds on channel activity are outlined in (Table  1).> -wrap-foot> Only spermidine and spermine at 5-10 mM induced a substantial reduction of single channel conductance while spermine alone also reduced the open probability.