Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
at study initiation
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "at study initiation" is correct and usable in written English.
It can be used in contexts related to research or clinical trials, indicating the point in time when a study begins. Example: "All participants were informed about the study procedures at study initiation to ensure their understanding and consent."
✓ Grammatically correct
Science
Alternative expressions(4)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
60 human-written examples
Other baseline characteristics (including percent-predicted FEV1 of about 40%) indicate a population with fairly severe disease (based on GOLD [Global Initiative for Chronic Obstructive Lung Disease] guidelines in effect at study initiation).
Science
The Alzheimer's Disease Neuroimaging Initiative (ADNI) phantom was scanned at each site at study initiation and termination to quantitatively estimate between-site and within-site differences.
Science
The margin of safety was evaluated in Beagles, which were 6 weeks old at study initiation.
Science
At study initiation, 98.3% of patients were taking 1 or more antidiabetes drugs, including oral medication and various types of insulin.
Science
The study design and the patients' baseline characteristics, including diabetes treatment at study initiation, are confounding factors limiting clinical conclusions on exenatide's glycemic effect in this patient population.
Science
Pursuit of adaptive design gains at least 20% to more than 30% genomic patient subset power when the genomic biomarker status is readily usable at study initiation, in comparison to when it is explored using the first-stage data of the same clinical trial.
The study sites tested the first panel just before or at study initiation.
Science
All dogs underwent a pre-treatment tumor biopsy and collection of PBMC at study initiation.
Science
Shortly after or at study initiation a follow-up training in finger-prick collection, HIV rapid testing and molecular amplification assay was conducted at the study site itself.
Science
The ICRL was responsible for the laboratory trainings, including state of the art hands-on training at study initiation in each site, provision of control panels and repeated testing of a subset of specimens for quality assessment purposes.
Science
Because the core phase of our study has been scheduled for a maximum of 3 years at study initiation, an extension phase is now planned in order to collect follow-up clinical data of the study cohort (progression index, time to conversion to clinically definite and chronic-progressive MS).
Science
Expert writing Tips
Best practice
When writing scientific papers, use "at study initiation" to clearly indicate the baseline conditions or characteristics of participants or procedures at the beginning of the research. For example, specify baseline measurements or participant demographics collected "at study initiation" to establish the context for subsequent results.
Common error
Avoid shifting tenses when describing events related to "at study initiation". Consistently use past tense for actions completed at the start of the study and present tense for describing ongoing conditions or current relevance. For example, use 'data were collected at study initiation' (past) and 'these data are now used for...' (present).
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "at study initiation" functions as a prepositional phrase that modifies a verb or noun, specifying the timing or point in time when something occurs in relation to a research study. Ludwig AI confirms the correctness of this phrase.
Frequent in
Science
100%
Less common in
News & Media
0%
Formal & Business
0%
Academia
0%
Ludwig's WRAP-UP
In summary, the phrase "at study initiation" is a grammatically sound and frequently used prepositional phrase primarily found within scientific and academic research contexts. It serves to pinpoint actions, conditions, or data collection occurring specifically when a study begins, providing a foundational reference for further analysis. According to Ludwig AI, the phrase is correct and widely used. Alternatives such as "at the beginning of the study" offer less formal substitutes, while phrases like "upon study commencement" maintain a similar level of formality. When employing this phrase, ensure temporal consistency and accuracy in describing the study's initial state.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
at the beginning of the study
Focuses on a more general phrasing using "beginning" instead of "initiation".
upon commencement of the study
Replaces "initiation" with the more formal term "commencement".
at the study's outset
Substitutes "initiation" with "outset", highlighting the initial stage.
when the study began
Uses a more straightforward and less formal phrasing.
at the start of the trial
Replaces "study" with "trial", suitable for clinical research contexts.
in the initial phase of the research
Elaborates on the phrase by specifying "initial phase".
at the inception of the study
Uses the more formal word "inception" to indicate the starting point.
at study commencement
Uses the word "commencement" instead of initiation, formal phrasing.
initially in the research project
Adds the adverb "initially" to indicate that something happened at first.
from the study's launch
Uses the word "launch" to indicate the start of a project.
FAQs
How can I replace "at study initiation" in a sentence?
Alternatives include "at the beginning of the study", "upon study commencement", or "at the study's outset", depending on the desired level of formality.
Is "at study initiation" appropriate for all types of writing?
While grammatically correct, "at study initiation" is most suited for scientific, academic, and formal writing. In more casual contexts, using "at the beginning of the study" might be more appropriate.
What information is typically documented "at study initiation"?
Commonly documented information includes baseline characteristics of participants, initial study protocols, and ethical approvals. This data helps provide context for interpreting subsequent results and ensuring transparency in research methodology.
What’s the difference between "at study initiation" and "at study entry"?
"At study initiation" refers to the overall commencement of the research project, while "at study entry" specifically relates to the point when individual participants are enrolled and begin their involvement in the study.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested