Exact(5)
tRNA genes show a mutation dynamics similar to other metazoans, with frequent compensatory mutations at stems.
This consideration diminishes the consequences of lower sugar yields from stems, and suggests that breeding targets for improved conversion should be directed at stems in order to capitalize on their higher sugar contents.
Based on the secondary structure estimation, 43% of nucleotide substitutions were deduced to be A < -- > G changes, 28% were T < -- > C and 19% A < -- > T, with most substitutions deduced to correspond to compensatory mutations occurring at stems (i.e. an A-U pairing in one species or group of species substituted by a G-C pairing in others).
The trend of higher divergence in stems and loops (vs. the mature miRNA) has been observed in other species (Hertel et al. 2006) and may be indicative of purifying selection against change to the functional component of the miRNA molecule (and/or a relaxation of constraint at stems and loops).
Several mismatched pairs were observed at stems (e.g. U-U in the amino acid acceptor arm of tRNA-Asn, which is conserved across the 21 studied tRNAs; and U-U or U-C in the amino acid acceptor arm of tRNA-Gln).
Similar(54)
The interventions succeeded at stemming the crisis.
The glue was so good at stemming bleeding that it was credited with saving many lives.
The police have proven peculiarly inept at stemming sporadic but recurrent bouts of sectarian strife.
The EU signed a €3bn (£2.3bn) deal with Turkey aimed at stemming the flow.
Recession has proved far more effective than policy at stemming the flow.
17.(S) Arditi told Levey that Palestinian Authority (PA) efforts at stemming terrorism within the territories were going quite well.
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