Interestingly, a subset of non-methylated CGIs associated with polycomb-mediated repression were not enriched for CFP1 [ 14], suggesting that, in some instances, the chromatin architecture at specific CGIs may restrict access of the ZF-CxxC domain.
Repetitive DNA may be dispersed throughout the genome or may be restricted at specific locations in a tandem configuration.
In addition, randomization at specific positions might be restricted to amino acids found in natural sequences as proposed by Jochens and Bornscheuer [ 24], thereby reducing the number of unwanted instable variants and thus the screening effort.
They may have restricted expression at specific cell types because they have putative promoter sites.
In contrast to the innate immune system, the adaptive immune system is composed of highly specialized systemic cells and defensive processes that are capable of preventing, or at least restricting, specific pathogen invasion.
Additionally, the developers claim that it provides high consistency [55] by trading off availability and consistency at low granularity in specific subsystems, restricting communication latencies, minimizing cluster size, maximizing consistency and availability during failover situations and automatic conflict resolution.
Their elites hired prominent white lawyers to fight their cause in the courts but, bowing to xenophobic political factions, Congress passed the Exclusion Act of 1882 -- the only federal law aimed at a specific nationality, which restricted the admission of Chinese into the United States.
High-coverage whole-genome sequence studies have so far focused on a limited number1 of geographically restricted populations2,3,4,5, or been targeted at specific diseases, such as cancer6.
In summary, we propose that the role of liquid viral inclusions is to spatially restrict vRNPs, increasing their concentration at specific sites to boost the kinetics of genome assembly.
Conceivably this action could be restricted to the vicinity of the transcription apparatus at specific genes.
The requirement for proteasomal degradation is thus not restricted to mitotic cells and does not require arrival at specific cell cycle phases.
