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The phrase "at significantly different" is correct and usable in written English.
It can be used when discussing comparisons or contrasts between two or more items, particularly in statistical or analytical contexts.
Example: "The results of the experiment showed that the two groups performed at significantly different levels."
Alternatives: "at markedly different" or "at notably different".
Exact(60)
Only the very best spinners can operate at significantly different paces according to the conditions.
The financial sector was perhaps clobbered even more, thanks to the government's decision to convert debts and credits from dollars into pesos at significantly different exchange rates.
The standard method involves comparison of data from two relatively close stations at significantly different altitude.
Twenty-eight miRNAs were expressed at significantly different levels compared to the non-autism control set in at least one of the autism samples.
Turn this to your advantage when buying, as you are likely to spot two fairly similar looking carpets in competing outlets at significantly different prices; for example, one at £15.99 per square metre and another at £29.99 per square metre.
Some said they expect they'll have trouble selling units in the same building at significantly different prices, and they'll have no control over condo fees that could rise in time and make lower-cost units suddenly exceed affordability limits.
Sometimes, said Kevin Reeves, the managing director of Mallorca Property Partners, a real estate search and advisory service, nearly identical properties are listed at significantly different prices.
While most miRNAs levels showed little variation across all samples suggesting that autism does not induce global dysfunction of miRNA expression, some miRNAs among the autistic samples were expressed at significantly different levels compared to the mean control value.
The induced electrostatic potential also cause forward and reverse ion exchange processes to proceed at significantly different rates, i.e. these are asymmetric.
These measurements reveal the presence of two distinct types of nickel oxide, which are reduced at significantly different temperatures on the different catalysts.
While a higher age limit would eliminate obstacles for some worthy candidates, a field that included older applicants would also make it harder to compare candidates fairly, since they might be at significantly different stages of their lives.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com