Sentence examples similar to at significant potencies from inspiring English sources

Although possessing reduced affinity at the D2 receptor, aporphines 15 and 18 show significant potency at both the D1 and 5-HT1A receptors.

Introduction of an amide substituent at the 6-position of the pyridone core resulted in a significant potency increase.

Significant potency gains were observed with small aliphatic substituents such as methyl, n-propyl, and cyclopropyl when placed at the C-2 position of the chromane.

Flavonoids showed a significant potency with values ranging from 0.1 to 5 mg ml−1.

However, it showed significant potency against non-multiplying organisms.

One of them, named HT61, is a quinolone-derived compound which presented significant potency.

On the other hand, significant potency differences were found for lipids with similar p Ka values.

Although the reason for these significant potency losses is unclear, the decrease in lipophilicity for these particular compounds may be partly responsible for the lower potencies observed.

Potency of AMG 334 at the cyno CGRP receptor is similar to that at the human receptor, but with significant reduced potency at dog, rabbit and rat receptors.

Macrocyclic compounds incorporating biphenyls were designed to improve physicochemical properties, at a significant cost in potency.

In the dust samples, 21 of the 24 samples tested showed significant binding potency at a concentration of 3 mg dust equivalent (DEQ /mL.