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The patient remained eligible for a new evaluation during the next attempt at sedation withdrawal.
In a retrospective analysis, Dr Veelo and colleagues [ 6] looked at sedation requirements in patients pre- and post-tracheostomy.
In addition, fNIRS is sensitive to different anesthetics such as propofol, sevoflurane, and desflurane at sedation and surgical doses [ 52– 52].
Since the first clinical trial looking at sedation with inhalational anaesthetic agents in the intensive care unit (ICU) [ 1], a number of studies have shown better control of sedation compared with intravenous drugs [ 2].
Similar(56)
However, though we observed a reduction in the percentage of scores at moderate sedation, this does not mean that the level of sedation was lower at the time CAM-ICU assessments were performed, as sedation was assessed much more frequently than delirium, which was assessed only twice daily at fixed time points.
In all volunteers two blood samples (2×1 ml) were taken at each sedation level for later measurement of plasma propofol concentrations with high performance liquid chromatography (HPLC).
Hence intra-individual variation at specific sedation levels is important.
T0 = Time between romifidine injection at the sedation and salbutamol inhalation.
The percentages of time at the sedation target and the propofol dosages were calculated.
Strategies aiming at light sedation are associated with decreased times on mechanical ventilation.
The equation is as follows: the percentage of time at the sedation target = (adequate sedation minutes/total minutes of sedation) × 100.
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