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Moreover, results revealed that CLEP-1bCLEP-1bgher anti-fatigue activity than LEP-1b at same doses but without statistical significance, especially CLEP-1b (200 mg/kg) had strong anti-fatigue effects.
Table 1 also reveals that about 97 % degradation of lindane (initial concentration 7.5 ppm) was achieved at FeSO4 dose of 40 mg ml−1 and H2O2 dose of 118 mg ml−1 at a pH of 3. Further, when pH of the reaction mixture was reduced to two at same doses of FeSO4 and H2O2, 83 % degradation of lindane was observed after 1 h of the reaction time.
For comparison, a second group received Met-Enk injections at same doses and intervals.
Seven days after the first treatment, all mice were injected again at same doses.
At same doses in DU145R80, we obtained a statistically significant 41% inhibition only with the higher dose of panobinostat, confirming that this cell line is slightly more resistant compared with DU145.
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Among the compound tested, 5 eIX showed protection from seizures in both the animal models at dose level of 30 mg/kg while 5 bII & 5 cII showed protection against scPTZ model at same dose level.
The decrease of plasma glucose in fructose-rich chow-fed rats produced by dioscorea was similar to that treated with Die-Huang-Wan at same dosing; while the other five herbs failed to produce same influence.
Compounds at 25 µM dose showed inhibitory activity, ranging from 85.817±, 83.023± to 72.864± % for MG, GC and C respectively compared to rutin at same dose (39.845 ± 1.48%) as positive control.
b - Limit duration for same agent(s) at same dose, route and schedule.
d - Parenteral to oral conversion(s) of same agent(s) at same dose and schedule.
Three weeks later, the mice were boosted with the vaccine at same dose as primed.
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