Exact(9)
This review lays the main focus on EMT in tumor cells and aims at recapitulating what is known about the molecular basis of EMT.
Current approaches to direct stem cell differentiation focus on systematically understanding the relative influences of microenvironmental perturbations and simultaneously engineering platforms aimed at recapitulating physicochemical aspects of tissue morphogenesis.
Although methods with limited structural flexibility have proven successful at recapitulating consensus binding sequences from wild-type complex structures, conformational flexibility is likely important for design and template-based modeling, where non-native conformations need to be sampled and accurately scored.
Comparing simulations against the Figure 3 experimental measurements showed the model to be successful at recapitulating the observed synergy between LY30 and TRAIL.
Our study in highly trained individuals utilized an intricate design aimed at recapitulating skeletal muscle stress and damage often seen in individuals with low training experience (Kraemer et al. 2009).
In a paper in BMC Biology, Bedford et al. [ 2] propose a mathematical model aimed at recapitulating the evolutionary trajectory of influenza H3N2 viruses, which are the subtype responsible for the majority of seasonal influenza cases from 1968 to date.
Similar(51)
We determined that inflorescence growth in Nymphoides proceeds by recapitulating at various positions one of three continuation axes: a rhizome, inflorescence, or floral continuation axis, all of which have sympodial, modular components.
We identified 1,136 RS-specific and 1,097 BP-specific RAD markers at 1,890 loci, recapitulating the marker density from our original study using RAD microarrays [11].
These results are reminiscent of the epiblast and visceral endoderm domains of the developing embryo (Supplementary Figure S1F), and suggest that hESC are capable of recapitulating at least some aspects of the supra-cellular order that characterizes in vivo development.
This meant that both central helices of BAX carry, by themselves, minimal structural information to insert into model lipid membranes and form pores, thereby recapitulating, at least in part, the behavior of full length BAX.
Interestingly and significantly, downregulation of CPT1A causes defects in cell motility, at least partially recapitulating the defects caused by downregulation of PAX3-FKHR.
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