at one dose

USAGE SUMMARY

The phrase "at one dose" is correct and usable in written English.
It can be used when discussing medication or substances, indicating the amount to be taken at a single time. Example: "The recommended administration is at one dose of 500 mg for adults."

✓ Grammatically correct

Science

Medicine

Research

Human-verified examples from authoritative sources

Exact Expressions

23 human-written examples

To determine whether the ASA prodrugs we synthesized (Fig.  1a and Additional file 2: Figure S1) inhibit the NFκB pathway, their activity was screened in MCF-7 breast cancer cells at one dose (50 μM) on NFκB-RE and NFκB target gene endpoints (Fig.  1b- e).

BMC Cancer

The synergy analysis based on the median effect methodology developed by Chou and Talalay [ 39] could not be performed on the in vivo data because the combination was only tested at one dose of gefitinib.

BMC Cancer

The newly synthesized compounds were evaluated against 60 human tumor cell lines at one dose and five dose concentration levels.

Bioorganic & Medicinal Chemistry Letters

For this aim an isotactic polypropylene and a random ethylene propylene copolymer were irradiated under vacuum at one dose rate and several absorbed doses after well defined solidification conditions.

Polymer

Our study is supported by Bilbao et al. who using adenovirus with a lacZ insert noted AII at one dose could increase lacZ expression detected by histology in larger rat hepatomas but not smaller hepatomas [29].

EJNMMI Research

Patients experiencing DLTs were eligible for further treatment at one dose tier below.

British Journal of Cancer

Human-verified similar examples from authoritative sources

Similar Expressions

37 human-written examples

Compound 12 was found to be highly active on HT29 (colon cancer) with cell promotion of −6.41% followed by MDA-MB-468 (breast cancer) with cell promotion of −6.34% and CCRF-CEM (leukemia) with cell promotion of −16.72% while the maximum cell promotion was observed on TK-10 (renal cancer), which showed 102.74% growth promotion at one-dose assay.

BioMed Research International

Compound 6 was found to be highly active on RXF 393 (renal) with cell promotion of −47.46% followed by MDA-MB-468 (breast cancer) with cell promotion of −29.14% and SK-OV-3 (ovarian cancer) with cell promotion of −29.09% while the maximum cell promotion was observed on TK-10 (renal cancer), which showed 28.55% growth promotion (71.45% growth inhibition) at one-dose assay.

BioMed Research International

Compound 8 was found to be highly active on SK-MEL-5 (melanoma) with cell promotion of −83.44% followed by RXF 393 (renal cancer) with cell promotion of −67.29% and SK-OV-3 (ovarian cancer) with cell promotion of −63.58% while the maximum cell promotion was observed on TK-10 (renal cancer), which showed 15.84% growth promotion (84.16% growth inhibition) at one-dose assay.

BioMed Research International

Compound 2 was found to be highly active on RXF 393 (renal cancer) with cell promotion of −53.60% followed by SK-MEL-5 (melanoma) with cell promotion of −29.66% and MDA-MB-468 (breast cancer) with cell promotion of −26.40% while the maximum cell promotion was observed on TK-10 (renal cancer), which showed 23.10% growth promotion (76.90% growth inhibition) at one-dose assay.

BioMed Research International

Compound 11 was found to be highly active on CAKI-1 (renal cancer) with cell promotion of −34.77% followed by MDA-MB-435 (melanoma) with cell promotion of −30.53% and SF-295 (CNS cancer) with cell promotion of −29.68% while the maximum cell promotion was observed on UACC-257 (melanoma), which showed 87.13% growth promotion (12.87% growth inhibition) at one-dose assay.

BioMed Research International

Expert writing Tips

Best practice

When discussing clinical trials or medical treatments, clearly specify if the treatment involves "at one dose" versus multiple doses to avoid ambiguity.

Common error

Avoid using "at one dose" when you actually mean a single dose within a larger, multi-dose regimen. Be precise: specify whether it's a one-time treatment or one instance within a series.

Linguistic Context

The phrase "at one dose" functions as a prepositional phrase specifying the quantity or manner in which a substance, typically a medication, is administered. As Ludwig AI explains, it indicates a single, distinct amount given at one time.

Expression frequency: Uncommon

Frequent in

Science

76%

News & Media

14%

Academia

10%

Less common in

Formal & Business

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, the phrase "at one dose" is a grammatically sound prepositional phrase predominantly used in scientific and medical literature to specify a single instance of substance administration. While not overly frequent, as indicated by Ludwig, its usage is clear and precise, contributing to its prevalence in formal contexts. Alternative phrases like "single dose administration" or "in a single dose" offer similar meaning, but the choice depends on the specific nuance needed. Ludwig AI confirms that it is correct and usable in written English.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

in a single dose

Similar meaning but with a different preposition.

just one dose

Adds emphasis to the fact that it is only one dose.

single dose administration

Emphasizes the act of giving a single dose.

one-time dosage

Highlights the singularity of the dosage.

one dose only

Emphasizes that no further doses are given.

a single administration

Focuses on the act of administering the medication once.

sole dosage

Highlights that this is the only dosage being used.

single application

Suitable when referring to topical or external treatments.

a solitary dose

Uses "solitary" to underscore the single instance.

unique dose

Implies that the dose is singular and perhaps specially tailored.

FAQs

How can I use "at one dose" in a sentence?

You can use "at one dose" to specify the quantity of a substance administered at a single time, such as in the sentence, "The drug was tested at one dose of 50mg".

What does "at one dose" mean in a medical context?

In a medical context, "at one dose" refers to administering a substance or medication in a single, distinct quantity at one particular time, rather than spread out over time or in multiple administrations.

Are there alternatives to saying "at one dose"?

Yes, you can use alternatives like "in a single dose", "one-time dosage", or "single administration" depending on the context. These phrases carry similar meanings but may fit better grammatically in certain sentences.

When is it appropriate to use "at one dose" versus "multiple doses"?

Use "at one dose" when describing a treatment given only once. Use "multiple doses" when describing a treatment regimen involving more than one administration, whether spaced apart or given together.