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This could bias the mutational spectrum of a gene towards micro-adaptive changes, as mutations at less important sites are more likely to produce functional proteins with slightly altered optima.
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If there is selection for secondary structures, one may expect higher constraint at structurally important (paired) than at structurally less important (unpaired) sites.
Her congregation numbered just five of the 580 synod members, the rest presumably preferring to worship or have breakfast.Miss Ozanne, who has previously marketed sanitary towels, fabric conditioner and Fairy Liquid, discovered that churchgoers thought the church was poor at spreading the Gospel, but good at the less important task of conducting weddings and looking after buildings.
Or is at least less important than standing and having a bit of a chat".
I don't much like the competition we may feel automatically as we grieve over the helpless child in a news report while the children or boys who just become men while they are shooting and being shot at, seem less important to us, because they aren't in our line of vision.
These interactions together with the translational activation in dKO myocardium suggest that enhanced muscle synthesis accounts for muscle hypertrophy, whereas reduced protein degradation by multi-ubiquitination is at least less important.
Note in this case that the levels of anthocyanins at maturity are less important than when treating at fruit set.
"You look again at what's important and at what's less important in life.
The thing that they are good at probably becomes less important than the way they lead their teams.
How the orchestra sounds at Avery Fisher Hall is less important than what it chooses to play and how it sees its mission.
By contrast, in the case of systems such as those in France and Sweden – offering full-time education and supervised homework sessions in schools – the role of additional help provided by parents at home becomes less important.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com