Exact(9)
A marked change in the structure of Si and SiO2/Si was observed in case of samples implanted at highest dose.
The dose of olprinone (0.2 mg/kg) used here were based on preliminary dose-response study (0.05 0.2 mg/kg), showing a significant protective effect of olprinone only at highest dose.
However at highest dose tested, 3-MT still caused significant behavioral activation in TAAR1 mutants and similar, albeit somewhat reduced in mutants, pattern of abnormal movements was observed in both genotypes after 36 µg of 3-MT (Figure 3; visual observations).
However at highest dose in SiHa cells it was observed a synergic effect.
PPIs used at highest dose showed an OR for HGD OAC of 0.9 (95% CI 0.3 to 2.3).
Absorption of TCDD delayed flowering time (up to 16 days at highest dose of TCDD) through presently undetermined mechanisms.
Similar(51)
However, subtle difference was recorded at higher dose.
Bioactive compounds are almost always toxic at higher dose.
Daidzein and puerarin at high dose increased significantly uterine weights.
All the compounds 5a f showed higher antiulcer activity at higher dose level of 500 µg/kg.
The C60 films are transformed into a form of amorphous carbon at high dose.
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