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Uptake of 3 and 4 in PR cells increased dramatically after 1 h, with higher accumulation at 4 h before decreasing by 8 h.

At the higher accumulation rates (> ~ 6 mg/kg/year), the growth rate decrease stabilizes at about 5%.

However, H. sp. at 30°C shows higher accumulation of lipids under nitrogen sufficient conditions (Figure 3E and F) compared to nitrogen starved conditions (Figure 3G and H).

Therefore, nanoparticles with mean diameters between 10 and 100 nm are generally preferred since they can attain much longer circulation times and, consequently, can achieve higher accumulation at the target site [54, 55].

Furthermore, polymeric micelles possess a nanoscale size range with a narrow distribution, and they can achieve higher accumulation at the target site through an enhanced permeation retention effect (EPR effect) [11].

Semi-quantitatively, the better electrochemical and electrochromic properties of both films take place predominantly at potentials where the higher accumulation of the radical cations (polarons and bipolarons) in the polymer structure involves great lattice reorganization.

In line with this, CD4 T cells with proliferative capacity showed higher accumulation at the site of infection than CD8 T cells two weeks post infection (although we can exclude that this bias in CD4 proliferation may in part reflect a bias inherent in the CD4 prime/boost mechanism).

Cinnamate, the immediate precursor of the phenylpropanoid pathway, showed higher accumulation at pre-veraison followed by a progressive reduction towards maturity in both cultivars.

Conversely, the distance-based species accumulation curve shows higher accumulation rates at larger scales, suggesting that distance between sites, and thus connectivity, becomes more important at these scales.

In UnicellAge, whether or not spontaneous decay of active and damaged material was included, asymmetric division was beneficial at higher damage accumulation rates in the absence of repair and damage being toxic, in agreement with [ 32] (Additional files 11, 12).

In spite of a sudden drop of cell concentration, an increase in dry cell mass led to high accumulation of xylitol at 48.7 g/l.

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