Sentence examples for at high dosing from inspiring English sources

However, there is still an unmet need to develop practical fiber formulations for water-soluble small molecule drugs needed at high dosing due to intrinsic low potency or desire for sustained prevention.

For instance, lapaquistat (TAK-475, Takeda), a SS inhibitor, progressed to phase III clinical trials, although its outcome in cancer remains to be established due to hepatotoxic effects at high dosing [276].

A recent study suggested that the mitochondrial effects of minocycline contribute to toxicity rather than tissue protection at high dosing in animals and humans (Mansson et al. 2007).

We know what happens at high doses.

At high doses, opposite effects of inhibition were observed.

At high doses, caffeine can be toxic to insects.

At high doses, it can cause the body to overheat.

At high doses, the agent simulates estrogen, Mr. Hodgen said.

But at high doses, the particles overload the clearance mechanisms.

Both also caused ataxia at high doses.

Malathion exerts cholinergic effects at high doses.