Exact(2)
All three hypotheses postulate that physical allelic variation between parents results in allelic interactions at given loci in F1 hybrids, which in turn causes heterosis.
However, the capacity to introduce specific directed changes at given loci is hampered by the fact that the major cellular repair pathway that occurs following Cas9-mediated DNA cleavage is the erroneous non-homologous end joining (NHEJ) pathway.
Similar(57)
Different isolates showed polymorphisms at the level of single nucleotides, number of repeats at a given loci, indels and synteny [ 12].
The method presented possesses the property that Type-I errors are no more likely to occur at a given locus than at an alternative.
Even high quality datasets contain errors where at least one allele at a given locus does not match with what we expect from the Mendelian laws.
With a simple sample, analysts look at two sets of peaks at a given locus: one for the victim and one for the perpetrator.
If a data point at a given locus is not significant at an FDR level of 5%, no transformation is performed.
At these populations, only two alleles at any given locus are simultaneously tested, without representing the genetic variability of the species (Holland 2007).
Here, d2 is the squared difference in number of repeat units between the two alleles at a given locus, standardized by the maximum observed value at that locus, and averaged across all measured loci [see 46], [63], [70].
2. The mutation at a given locus is a function of the alleles at all other loci so is inherently an interacting many-body process.
Local hybrid assembly supported 7,708 loci, that is, at least one assembled contig supported the predicted SV at a given locus.
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