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Life-cycle assessment (LCA) methodology has been used for the quantification and evaluation of the environmental impacts of the new production line (L6) considering the designed goals proposed and those achieved at first trimester of 2011 compared to the former production lines.
In the INMA-Sabadell cohort maternal DNA samples were extracted from blood obtained at first trimester of pregnancy.
Maternal diet was obtained at first trimester through a validated food frequency questionnaire.
The gestational age was determined from last menstrual period and corrected by ultrasound at first trimester.
GA was calculated according to last menstrual period and confirmed by prenatal ultrasound at first trimester.
The response criteria can only be applied to those patients with an initial DAS28>3.2 at first trimester (n = 75).
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Results: Women with multiple thrombophilic factors had a significant lower birth weight (1568.33±146.8 g versus 2546.45±438 g), higher 24 h mean diastolic blood pressure at second trimester (76.3±12.5 mmHg versus 65.2±7.8 mmHg) and higher RI of uterine arteries (0.69±0.05 versus 0.50±0.15) than women with single thrombophilic factor.
Significant ethnic differences between mothers were not reflected in fetal biometry at second trimester.
We selected studies in which placenta previa was diagnosed or recorded at third trimester or during delivery.
However, the only significant BPb effects were with BPb at third trimester of pregnancy and BPb measured simultaneously with IQ tests.
After embryo reduction or spontaneous miscarriage, at second trimester ultrasound (10.0 13.6 weeks) there were 497 (10.2%) ongoing twin pregnancies, and 470 of them gave live births (9.6%).
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