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The cells were then incubated with NDs and HFNDs at equivalent concentrations of HCPT.
As shown in Figure 7, at equivalent concentrations of HCPT, the HCPT-loaded PEG-b-PLA NPs showed higher cytotoxicity than the HCPT-loaded PLA NPs at equivalent concentrations of HCPT.
P5D and P7D were specifically cleaved by active MMP-2 and all conjugates showed significantly better cell viability than doxorubicin at equivalent concentrations.
Neither dap-MWCNTs at lower concentrations (up to 50 μg/ml), nor o-MWCNTs, at equivalent concentrations, respectively affected the viability of PMØ, while higher concentrations triggered apoptosis.
Both PGA-PTX-DOX and PG-PTX-bz-DOX-PEG nano-sized conjugates exhibited superior anti-tumor efficacy and safety compared to the combination of the free drugs, at equivalent concentrations.
In cotton rats, at equivalent concentrations, motavizumab reduced pulmonary RSV titers to up to 100-fold lower levels than did palivizumab and, unlike palivizumab, motavizumab very potently inhibited viral replication in the upper respiratory tract.
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HUVEC (15×104 cells/100 µl) were exposed to HPMA copolymer-ALN-TNP-470 conjugato or to combinations of free ALN and TNP-470 at equivalent concentration and were added to the upper chamber of the transwell.
Furthermore, killing curves experiments, at equivalent concentration of compound 1, showed an immediate decrease in the bacterial count, and no viable cells were observed after 120 min, showing a fast bactericidal effect (data not shown) presumably not solely related to the inactivation of PBPs.
Vehicle (DMSO) was added to control wells at equivalent concentration (0.1% maximum concentration).
We prepared the mixed cDNAs from the heart, liver, brain, spleen and kidneys of silver carp at equivalent concentration.
Negative controls, where the primary antibodies were substituted with isotype matched irrelevant monoclonal antibodies at equivalent concentration, were routinely performed.
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