Sentence examples for at distinct steps from inspiring English sources

Each of these genes is required at distinct steps in the trafficking proteins from the apical membrane to the lysosome.

Electron microscopy analyses indicate that endosome maturation is impaired at distinct steps by hrs and stam mutations.

To date, the subtle changes that occur at distinct steps in the transport of RNA-protein complexes, particularly osk and its known trans-acting proteins, have been impervious to biochemical analyses.

Thus, our results highlight the requirement for wild-type huntingtin at distinct steps along the secretory pathway.

When combined with previous findings, these results provide evidence that the different branches of the ERAD pathway regulate ergosterol synthesis at distinct steps.

It is also increasingly appreciated that a tumour suppressor may act at distinct steps in the neoplastic process, such as initiation, invasion or metastasis.

This allows the algorithm to be compared and optimized at two distinct steps: point anomaly detection, and contextual anomaly detection.

Using growth curves and electron microscopy in conjunction with inhibitors, we show that that PI3Ks additionally regulate morphogenesis at two distinct steps: immature to mature virion (IMV) transition, and IMV envelopment to form intracellular enveloped virions (IEV).

For the 40 C-terminal residues, no lipid binding is observed at low lipid:αS ratios, but as previously observed for WT, considerable resonance attenuation is seen at high ratios, with distinct steps at locations that coincide with the positions of proline residues (at P120 and P128).

The first requires breaking the task at hand into distinct steps and performing them one at a time.

The reaction shows a primary kinetic isotope effect of 4.3 at the benzylic C H position together with a reversible H D exchange at the same position, which indicates that there are at least two distinct steps in which the corresponding C H bonds are broken.