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Norepinephrine that diffuses away from local nerve endings can act on adrenergic receptors at distant sites.
Of 12 complete responses, six relapsed, all at distant sites, and two died during initial therapy.
Histological characterization of tumors arising at distant sites following vessel seeding.
Finally, the use of immunohistochemistry for the confirmation of metastatic renal cell carcinoma presenting at distant sites will be discussed.
With this discovery emerged the concept that chemical messages could act at distant sites to regulate bodily functions.
The ability of cancer cells to establish lethal metastatic lesions requires the survival and expansion of single cancer cells at distant sites.
Such macrophages, in turn, can act at distant sites to suppress the actions of T lymphocytes that previously succeeded in keeping the implanted tumors under control.
Scientists postulate that bacteria from gum infections travel through the bloodstream to trigger inflammation in organs and tissues at distant sites.
Gene transcription rates are regulated by transcription factors, which bind to promoter regions close to the specific gene or to enhancer regions at distant sites.
Because they are released into the capillary system of the bloodstream and act at distant sites of the body, these are called neurohormones.
Exosomes enable intercellular communication by transporting genetic material, proteins and lipids to cells in their vicinity or at distant sites, and subsequently regulating functions of targeted cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com