Exact(11)
To check the robustness of ARGOT in predicting the correct function at different sequence similarities we have plotted the ROC100 in 3(a) with no restrictions applied to the sequence identity shared between query and hits.
Regarding the test set YEAST, the robustness of ARGOT was checked at different sequence similarities and we report in Fig. 4(a) the ROC100 plot, where no restrictions were applied to sequence identity between query and hits, and in 4(b) the ROC40 plot of over 600 sequences sharing no more than 40% sequence identity with first BLAST hits.
Patients received two kinds of therapies (EGFR-TKIs and chemotherapy) at different sequence were included.
A total of 136,000 reftigs (86.7%) were longer than 200 bp and used for clustering at different sequence identity thresholds.
We simulated reads at different sequence depths for variant detection and found that most of the late and intermediate mutations would have been missed entirely by bulk sequencing at standard coverage depth.
Only non-redundant protein sequences were retained as annotated by the Vector Alignment Search Tool in the non-redundant PDB chain set at different sequence similarity cut-offs [ 22].
Similar(49)
We created in silico metagenomes mimicking various platforms at different sequencing depths.
Figure 3 shows the average PCC of the different dissimilarity measures at different sequencing depths and tuple sizes.
Figure 3B shows the distribution of the detected binding sites at different sequencing depths for a single binding site.
In total 16 different individuals originated from 13 populations of Sus scrofa were sequenced at different sequencing centers using the Illumina HiSeq platform.
All PCR products were purified using ExoSAP-It (Affymetrix) and sequenced in both directions using the original PCR primers with BigDye v3.1 at different sequencing services.
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