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Therefore, the first aim of this study was to compare adipocyte size and mRNA expression between different equine AT depots with special interest in the nuchal AT region.
Freshly isolated AT depots were fixed for 20 min in PBS containing 4% paraformaldehyde at 4 °C.
AT, adipose tissue Expression of M1 and M2 markers was comparable in CLP-fed and CLP-restricted mice in all AT depots.
Reductions in AT depots were associated with improvements in biomarkers.
In conclusion, different mRNA expression of inflammation-related genes in different AT depots suggests that AT depots may be a driving force for total body inflammation.
Elevated levels of SFAs in both epididymal and inguinal AT depots in the Aa and Cpn + Aa groups suggested an increased proinflammatory potential of these AT depots.
The evidence for a causal role of AT depots from surgical studies, therefore, is not conclusive.
Chronic Cpn infection displayed only minor effects on transcriptomics and fatty acids of the AT depots.
Our hypothesis was that mRNA expression of inflammation-related genes varied across AT depots.
Obesity is characterized by adipocyte hypertrophy but also by the accumulation of macrophages in AT depots.
AT depots are dispersed throughout the body and are closely associated with several organs [ 3].
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