Exact(3)
Expiry at date of analysis was of borderline significance.
In addition, expiry at date of analysis was also a risk factor for poor quality when both components were considered.
Adjusting for expiry at date of analysis led to no major changes in ORs, with the exception of Europe as stated country of manufacture where the OR decreased from 3.0 to 0.9 (Supplemental Table 2).
Similar(5)
The interim analysis included 114 randomised patients (approximately two-thirds of the initially planned sample size) from the target population who should have completed the treatment period (week 12) at the date of analysis as well as all patients having completed week 24 at the cut-off date.
Two hundred and thirty-six (91 %) patients had discontinued EM treatment at the date of analysis.
At the date of analysis the ATP-binding cassette (ABC) transporters were not classified as genes with "transporter activity".
Of the 44 patients treated, 15 are still alive at the date of analysis (3 CR, 9 PR, 2 SD and 1 PD).
At the date of analysis, 18 patients showed progressive disease (PD) as evaluated by RECIST version 1.1 and 10 patients had died due to progression of RCC.
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