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However, as it has been reported that transcriptional recruitment at certain locus may affect the expression of adjacent genes, we do not exclude the possibility that the acquirement of the transcription activity in the CCAT1-L locus during CRC pathogenesis may also contribute to the regulation of MYC transcription.
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During the initial SSR genotyping of the IR29/Pokkali QTL population, multiple Pokkali alleles were observed between RILs at certain loci.
Moreover, the genome wide analysis of DNA methylation at CpG sites in ESC and iPSC indicates that at certain loci iPSCs remain incompletely or aberrantly reprogrammed, and those are especially enriched at genes involved in developmental processes [71].
Analysis of the distribution and density of SNPs in the genomes suggest that recombination has generated allelic variation at certain loci in the BM407 chromosome, thereby increasing the apparent level of diversity.
In addition, our results have implications for endangered species such as the California gnatcatcher, where lack of differentiation at certain loci (e.g. mtDNA; [57]) may not reflect important genetic differentiation detectable with other markers such as microsatellites.
In practice, some sequencing errors systematically occur at certain loci on certain instruments [ 18].
Our results show that a large number of amino acid polymorphisms can occur at certain loci, underbalancing selection.
These numbers differ slightly from those (i.e., n = 73 individuals at 9-14 loci) previously reported [ 27], reflecting the additional genotyping of some individuals at certain loci.
In contrast, the model of over-dominance suggests that the presence of heterozygosity at certain loci is advantageous in itself [ 10].
In several electrophorograms, overlapping peaks were detected at certain loci, even after repeated processing (repeated nucleic acid extraction, RT-PCR, and sequencing) of the samples.
In the first round of genome reprogramming, sex-specific methylation patterns are established at certain loci in the male and female germline, respectively.
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