The cleavage of arrestin-2 by caspases at Asp-380 generates a truncated form lacking the C-tail, arrestin-21 380 arrestin-21 380014).
On both of these days ΔH showed a midday peak at equatorial and low latitude stations and reversing to midday minimum at stations poleward from the Sq focus region e.g. at BMT, in the north and at ASP and CNB in the south.
Therefore we mutated alternative potential caspase cleavage motifs and found that βNAC is instead cleaved at Asp 175.
The large and small subunits are the result of cleavage of the proenzyme at Asp (D) residues, which are homologous to human Asp316 and Asp330 (based on equivalent sites described in human caspase 2).
Caspase cleavage of GFAP at Asp produces two major cleavage products.
During the maturation process, procaspase-3 is first cut at Asp-175 and forms the p20/p12 complex, which is catalytically active and can undergo autocleavage at Asp-28 to remove the prodomain and generate the mature p17/p12 caspase-3.
Immunohistochemical studies in cases with Down syndrome demonstrated plaque-Aβ starting at Asp-1 or pyroGlu-3 [ 48].
The first peak originated from cleavage at Asp within the loop formed by the Cys Cys disulfide pair.
It is important to note that the conformational shift occurs without cleavage of the polypeptide chain at Asp.
Plectin, a cytolinker responsible for the mechanical stability of the cytoskeleton, is cleaved by caspase-8 at ASP 2395.
