Sentence examples for at an earlier passage from inspiring English sources

This concern emerged from our observation that IPF myofibroblasts showed morphological changes characteristic of senescence [42] at an earlier passage than did controls (data not shown).

Thus, upon continued propagation, vHMEC-ras cells become increasingly genomically unstable, manifesting genomic changes at an earlier passage and an increased frequency than detected in cultured vHMEC.

To determine whether the process of differentiation resulted in myogenic cells losing their mtDNA mutation, myoblasts from Patients 2 and 3 were differentiated into myotubes at an earlier passage (Table  4).

To explain the results observed, we hypothesized that the abnormal centrosomes in cell culture-induced senescent MEFs at passage 6 and NEDD1 depletion-induced senescent MEFs at an earlier passage may have been fragmented or incorrectly assembled, rather than overamplified.

As an interim measure we have adapted a hESC line derived under nearly xeno-free condition [30] to defined medium conditions using CellStart as a substrate at an early passage culture.

To assess whether oxidative stress affects the levels of Zfp277 and PcG proteins, we treated MEFs at an early passage (P-2) with hydrogen peroxide (H2O2) which induces the generation of ROS [35].

The A549 human lung adenocarcinoma cells, obtained from ATCC (American Type Culture Collection, Manassas VA, USA) and used at an early passage number, were cultured in DME with 10% serum and penicillin, streptomycin and gentamicin antibiotics.

We would recommend that cells expressing these damage phenotypes at an early passage not be injected into injury sites or used for mechanistic injury studies due to problems with comparability.

Biased gene expression associated with such chromosomal aberrations has also been observed in some of the hiPSC lines analysed, as a result of culture adaptation, although biased gene expression was also found at an early passage of one hiPSC line (Mayshar et al., 2010).

Parental MCF-10A cells were obtained from the stock collection at the Garvan Institute of Medical Research, Sydney, and represent an early passage population from an import from ATCC.

Heinrich Kreutz studied the orbits of the three great comets, and developed the idea that the three comets were fragments of a much larger progenitor comet which had broken up at an earlier perihelion passage.