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Thus, activation of oncogenes and/or loss of tumor suppressor genes might be necessary at a subsequent step, enabling binucleated tetraploid cells to survive, proliferate and potentially give rise to aneuploid cells.
All inhibitors reduced MDM infection, demonstrating that although these reagents do not prevent HIV-1+ T cell capture by MDM, they act at a subsequent step to block viral entry into MDM.
Since some L1 ORF1p mutant proteins, in which neither the binding affinity for RNA nor the RNP formation have been altered, exhibit a reduced retrotransposition rate [ 10, 32], it has been suggested that this protein having NAC activity should have an additional function in the TPRT mechanism at a subsequent step of that involving the RNP formation.
As individual level ratings of social support and social capital are likely to be correlated, social capital was included at a subsequent step in the regression model to enhance our capacity to examine the benefits of community level support above those attributable to an individual's propensity for close social relationships.
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In a subsequent step, samples at 6% consistency (w:w) were submitted to a peroxide-reinforced alkaline extraction using 1% (w:w) sodium hydroxide and 3% (w:w) hydrogen peroxide (also with respect to sample dry weight) at 80°C for 90 min, followed by water washing [ 29].
Lipid droplet (LD) and membrane fractions were purified by a subsequent step of centrifuging at 100,000 × g.
At any subsequent step the variable giving the highest increment to AUC is entered.
At any subsequent step the variable giving the highest increment to AUC was entered.
We propose that this is, at a subsequent activation step, used by an extended form of the TM subunits to reach the target membrane with their fusion peptides.
This might, at a subsequent activation step, guide the formation of an extended (pre-hairpin) form of the TM subunits and the presentation of their fusion peptides to the target membrane.
At each subsequent step the tag pair with the next highest correlation value is identified.
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