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At a single unit level, this modulation is likely to be reflected in membrane potential modulations, since the LFP was shown to strongly correlate with the membrane potential (Lampl et al. 1999; Poulet and Petersen 2008; Okun et al. 2010).
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In the self-organization perspective that we propose, the spatial responses first emerge spontaneously, at the single unit level, with no engineering required.
First, it was conducted at a single unit.
For example, at the macro level a country is treated as a single unit, whereas meso-level analyses look at spatial differences between sub regions within a country.
Instead, we found that the increase in global response amplitude in mel-low could be attributed to a similar change at the single-unit level, with >75% of units showing greater light-evoked firing in this condition.
A similar effect was observed at the single-unit level regarding the fraction of spikes participating in single-unit bursts, while burst properties were not significantly affected.
For detection of bursts at the single-unit level, bursts were defined as 3 or more spikes at a minimum of 50 Hz (see 'single_unit_bursts.m' in Source code 1).
The self-organization process we consider at the single-unit level can be described in analytical terms as an unsupervised optimization process, if one neglects the collateral interactions that are presumed to align the grids (Si et al., 2012).
Primary dendrites were initiated at 0 hour with a single unit without a branch.
(G ) Acute effect of baclofen on firing rate at the single-unit level.
These data indicate that firing synchrony of spontaneous activity is maintained at the network level, despite large changes in burst patterns at the single-unit level.
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