Sentence examples for at a nuclear level from inspiring English sources

Furthermore, a precise analysis at a nuclear level, such as the raphe nucleus, would be informative.

CLDN1 has been identified within the nucleus of gastric cancer AGS cells in vitro, suggesting a regulatory role of CLDN1 on cell proliferation, migration and invasiveness at a nuclear level [ 36].

The fraction of tumour cells positive at a cytoplasmic (for bcl-2), cytoplasmic and nuclear (for p16ink4A), or at a nuclear level (for the other antigens) was evaluated independently by two observers by scoring a total of 1000 3000 tumour cells and was defined as the percentage ratio between positive and total number of tumour cells.

These findings prompt the hypothesis that, at least at nuclear level, HBR may have acted following the hydrolysis of its grafted moieties.

Concurrently, we've fielded a general-purpose force capable of engaging an enemy at a non-nuclear level.

Previous data indicate that Hxk2, Mig1 and Snf1 form a complex at the nuclear level and that Hxk2 functions as a bridge between Snf1 and Mig1, interacting with Snf1 to inhibit Mig1 phosphorylation at Ser under high-glucose conditions [ 9].

Recent studies from our and other laboratories demonstrated that p53 protein, the product of TP53 gene, in response to an oxidative stress not only behaves as a transcription factor at nuclear level, but can also translocate at mitochondrial level [ 18- 20].

At nuclear level, A β injection induced a significant upregulation of NF- κB (17.5 ± 1.9 versus 1.3 ± 0.8, P < 0.001, Figures 2(a) and 2(b)) compared to vehicle-treated mice, as demonstrated by EMSA analysis, indicating a marked A β-induced neuroinflammatory response in the hippocampi and 2(b)).

In monkey and human SNc, astrocytes were identified by GFAP immunofluorescence, and exhibited intense labeling for angiotensinogen/angiotensin located in the cytoplasm, without a clear labeling at the nuclear level (Fig.  6a h).

Functional dissection should help to unravel the remaining mysteries of PARP-1 as a signalling molecule at the nuclear level in T cells and might be essential for future development of new therapeutic approaches targeting PARP-1 in the acquired immune response.

They activate specific sets of genes via a number of transcription factors at the nuclear level, of which NF-κB appears to have a central role in sepsis [ 40].